If you want to create your own private cloud and be able to share and transfer large files without restrictions, then build your own FTP server on Windows 10.

FTP servers use TCP ports 20 and 21 to send and receive information, so you won't have any conflicts with the web server running on TCP port 80.

NVMe-over-TCP is an extremely similar concept to iSCSI, except it's aimed specifically at NVMe drives and leveraging their high-speed capabilities.