Inter Miami will be up against the challenge of Puma UNAM in their upcoming Leagues Cup. Inter Miami will have a tough clash on their hands, with the team expected to be without skipper Lionel Messi,

The odds of making it beyond the group stage are incredibly slim for both organizations, despite their impressive performances in their respective domestic leagues this season. Former Aston Villa boss Dean Smith has pulled Charlotte up to seventh in MLS ' Eastern Conference, while Monterrey is just three points off the summit in Liga MX's Apertura.

The Red Bulls will need a win and a little bit of help to move on to the knockout stage. They started the tournament off on the right foot, beating Chivas de Guadalajara last Thursday, but only salvaged a point against Monterrey this past Sunday, losing in penalties.