Milestone articles have highlighted the frequency and types of statistical errors in research,1–5 yet fundamental errors ...

Heightened interest in left ventricular thrombus (LVT) stems from the consistent association of subsequent stroke and ...

Background Mobility limitation is prevalent in patients with heart failure (HF), but the dose-response relationship between ...

Legalisation of medical and recreational cannabis commerce is spreading around the world, associated with increased use1 and ...

Studies of the epidemiology of heart failure in the general population can inform assessments of disease burden, research, public health policy and health system care delivery. We performed a ...

Background and objective Prior studies have suggested that patients with premature ventricular complexes (PVCs) may have an ...

Diabetes mellitus is highly prevalent in patients with coronary atherosclerosis. As a result of several factors, including a ...

Results 257,948 patients underwent troponin assessment. During a median follow-up of 1,198 (IQR, 514–1,866) days, there were 55,850 (21.7%) deaths. Using multivariable-adjusted restricted cubic spline ...

Clinical guidelines are developed by professional societies and also, in England, by an independent non-departmental public body, the National Institute for Health and Care Excellence (NICE).

Background Percutaneous coronary intervention (PCI) is frequently used for patients with chronic coronary syndrome (CCS). However, the role of PCI beyond symptom relief in CCS remains controversial.

Background Cardiovascular disease (CVD) risk increases with age. Statins reduce cardiovascular risk but their effects are less certain at older ages. We assessed the long-term effects and ...

The ‘Fontan circulation' has evolved to include a variety of surgical procedures designed to overcome the absence of two distinct ventricular chambers.1 w1–w3 Inherent to this circulation is chronic ...