Detectives in Anderson County are asking for help finding a missing man who they say has a severe case of autism.

The U.S. Supreme Court upheld Tennessee’s ban on gender-affirming care for transgender minors. Here's what to know.

An 18-year-old was killed in a fiery crash along an interstate in South Carolina, according to fire officials in Colleton County.

One person is dead after a vehicle hit a tree Thursday in Anderson County, South Carolina. The coroner's office was called ...

The president has signed an executive order to keep TikTok running in the U.S. for another 90 days to give his administration more time to broker a deal to bring the social media platform under ...

Investigators are looking at the wreckage to determine what could have caused one of the worst air crashes India has seen in decades.

Clemson University announced Thursday that Marquise Henderson has been dismissed from the team. A Clemson football spokesman released the following statement to WYFF News 4: "Clemson has made the ...

The scam affected more than 400 people worldwide, including dozens of Americans, and caused millions of dollars in losses, ...

The West Union Police Department in South Carolina says an investigation at a restaurant on Wednesday was "not an ICE raid." ...

A part of Interstate 40 near the North Carolina-Tennessee state line remains closed and officials said Thursday there is no timeline for it to be reopened. Both directions of the interstate were shut ...

One man was killed and another man was injured Thursday morning when their small plane crashed near the Beverly, ...

A federal judge said Wednesday that prosecutors can proceed with a hate crime charge against a man accused of hurling Molotov cocktails at a group of people demonstrating in Boulder, Colorado, in ...