Using all-atom simulations of model mycomembranes, the work reports compelling structural insights into how α-mycolic acids and outer leaflet lipids (PDIM and PAT) shape membrane organisation. The ...
Two-dimensional liquid chromatography (2D-LC) improves chromatographic performance, with LCxLC providing extensive ...
Transition between cell states of sensitivity reveals molecular vulnerability of drug-tolerant cells
Cancer cells evade apoptosis by transitioning between cell states of drug-sensitivity. Necroptosis vulnerability state was uncovered, and mathematical models revealed why drug holiday fails, while ...
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